Web8 mei 2024 · Atorvastatin is the most common cause of clinically significant liver injury in this drug class. We report a case of severe, asymptomatic liver injury in a hepatocellular pattern in a 71-year-old man occurring within 3 months of switching from simvastatin to high-intensity atorvastatin therapy. Hepatitis improved rapidly with cessation of ... WebDrug Name atorvastatin calcium (ah tor' va stah tin) Lipitor Pregnancy Category X Drug classes Antihyper lipidemic HMGCoA reductase inhibitor. Dosages ADULTS Initially, 10 mg PO once daily without regard to meals; for maintenance, 1080 mg PO daily. May be combined with bile acid binding resin. PEDIATRIC PATIENTS 1017 YR Initially, 10 mg …
Scenario: Lipid therapy - primary prevention of CVD
WebKim SH, Park K, Hong SJ, et al. Efficacy and tolerability of a generic and a branded formulation of atorvastatin 20 mg/d in hypercholesterolemic Korean adults at high risk … WebFamilial hypercholesterolemia. Statins may be less effective in reducing LDL cholesterol in people with familial hypercholesterolemia, especially those with homozygous deficiencies. These people have defects usually in either the LDL receptor or apolipoprotein B genes, both of which are responsible for LDL clearance from the blood. texture play
How Genetic Variants in Children with Familial Hypercholesterolemia …
Web1 dag geleden · 1. I ntroduction. Heterozygous familial hypercholesterolemia (FH) is the most common codominant monogenic dyslipidemia, affecting about 1 in 250 individuals [1].FH causing mutations in the LDL-receptor gene (LDLR), apolipoprotein B gene (APOB) or proprotein convertase subtilisin/kexin type 9 gene (PCSK9) lead to high LDL-C levels … WebStatins are microorganism derived drugs that greatly impair the cell synthesis of cholesterol by competitively inhibiting the activity of the enzyme HMG-CoA reductase. Statins, … Web1 mrt. 2008 · Atorvastatin therapy resulted in a significant reduction in total cholesterol, TGs, LDL-cholesterol, apoB concentrations and BP levels in both patient groups. Interestingly, atorvastatin therapy resulted in improved insulin resistance (as reflected by a significant drop in serum insulin and consequently HOMA-IR) in group A and B ( Table 2 ). texture powder for hair walmart