Jes6-1a12
Web1 gen 2014 · Binding by JES6-1A12 would thus convert complexed IL-2 into a very weak agonist, reinforcing the advantage of T regulatory cells (displaying the high affinity αβγ heterotrimeric receptor) to capture the cytokine by competition and expand over effector cells, ultimately resulting in the observed strong tolerogenic effect of this antibody. WebMouse IL-2 is a 17.2 kD protein containing 149 amino acid residues. Recombinant mouse IL-2 (Cat. No. 550069) is supplied as a frozen liquid comprised of 0.22 µm sterile-filtered aqueous buffered solution and bovine serum albumin, with no preservatives. Recombinant mouse IL-2 is ≥ 95% pure as determined by SDS-PAGE, and an absorbance assay ...
Jes6-1a12
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WebmAb JES6-1A12 was not able to inhibit mIL-2 capture by the two other antibodies and its binding was not inhibited by a large excess of any of them (Fig. 2), indicating that the two classes of antibodies recognize different antigenic regions on mIL-2 surface. Lack of competition between JES6-1A12 and S4B6 The JES6-1A12 antibody is a neutralizing antibody. Mouse IL-2 (also known as TCGF) is a 17 kDa factor produced mainly by activated CD4+ T cells. IL-2 induces cell cycle progression of resting cells in an antigen non-specific manner and allows clonal expansion of activated T cells.
WebThe JES6-1A12 antibody is a neutralizing antibody. Mouse IL-2 (also known as TCGF) is a 17 kDa factor produced mainly by activated CD4+ T cells. IL-2 induces cell cycle … WebThese antibodies target IL-2 in Human, Mouse, Rat, Porcine and Feline samples. Our IL-2 monoclonal, polyclonal, recombinant monoclonal and recombinant polyclonal antibodies are developed in Rat, Rabbit, Mouse, Goat and Sheep. These antibodies have been verified by Cell treatment and Neutralization to confirm specificity to IL-2.
Web1 dic 2008 · We could provide such evidence because we were able to deliberately expand T reg cell population in vivo by use of immunocomplexes of rmIL-2 and anti-mouse IL-2 mAb JES6-1A12, which were previously shown to stimulate the expansion of T reg cells , before inoculation of BCL1 cells, which indeed exacerbated the disease. WebAnti Il 2 Jes6 1a12 Antibody, supplied by BioLegend, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more. Home > Search Results > BioLegend > anti il 2 jes6 1a12 antibody. anti il 2 jes6 1a12 antibody About; News; Press ...
Web11 apr 2024 · 6RXUFH Monoclonal Rat IgG1 Clone # JES61A12 3XULILFDWLRQ Protein A or G purified from hybridoma culture supernatant ,PPXQRJHQ ( FROLderived recombinant mouse IL2 (QGRWR[LQ/HYHO <0.10 EU per 1 …
WebMouse IL-2 Antibody Summary. Detects mouse IL-2 in ELISAs. Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either … snowy christmas scenes imagesWebProduct Description. Rat anti mouse IL-2, clone JES6-1A12 recognizes mouse Interleukin-2. IL-2 is a cytokine required for T-cell proliferation. Rat anti mouse IL-2, clone JES6-1A12 … snowy christmas sceneWebELISA Detection1-3 or ELISPOT Detection4-6: The biotinylated JES6-5H4 antibody is useful as a detection antibody for a sandwich ELISA or ELISPOT assay, when used in conjunction with the purified JES6-1A12 antibody (Cat. Nos. 503701 & 503702) as capture antibody and recombinant mouse IL-2 (Cat. No. 575409) as the standard. snowy christmas background clipartWebRat monoclonal antibody raised against recombinant Il2. IgGy Antibody Selector – Quickly search hundreds of thousands of antibodies available for purchase from VWR by … snowy classicWeb12 apr 2024 · Anti-IL-2 Abs (JES6-1A12 and S4B6), anti-CD25 (PC-61.5.3), or rIL-6 was added at the indicated concentrations for an additional 72 hours. snowy christmas holidays 2022Web19 nov 2013 · On the other hand, the simultaneous blockade of the interactions with α and β/γ chains by JES6-1A12 mAb provides a rationale for its strong immunoregulatory activity observed in diverse scenarios like autoimmune diseases therapy and transplantation, 10, 11, 13 and tolerance induction against therapeutic proteins. 12 Such dual inhibition of … snowy comparative and superlativeWeb15 apr 2016 · Cytokine ELISA: Interferon gamma (INF-g) was measured by ELISA using the capture Ab JES6-1A12 and the biotinylated detection Ab JES6-5H4 (BD Pharmingen™, Belgium). Briefly, Secreted INF-g upon activation of splenocytes was measured in an ELISA using the capture antibody JES6-1A12 and the biotinylated detection antibody JES6-5H4 … snowy coconut frost wallflower