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Promis-hfpef研究

WebApr 14, 2024 · 综上所述,该研究构建了一种全新的hfpef小鼠模型,高度复制了临床hfpef患者的病理表型。 以此为基础,揭示NLRP3炎症小体和线粒体功能障碍是HFpEF发生发展的重要驱动因素,并证实提升酮体β-OHB水平可调控上述线粒体-炎症环路,改善HFpEF症状( … Web事实上,美国国家心脏、肺和血液研究所赞助的wise(女性缺血综合征评估)研究的数据表明,inoca患者的预后更差,低cfr是mace的可靠独立预测因子[5]。 这些发现随后被扩展,发现CFR降低(CFR<2)是女性和男性MACE的有力增量预测因子[2]。

PROMIS: Clinical Outcomes Assessment - Funded Research

WebJan 21, 2024 · Using the prospective multinational PROMIS-HFpEF study (Prevalence of Microvascular Dysfunction in HFpEF; n = 182; 54.6% women), we compared clinical and biomarker correlates of CMD (defined as coronary flow reserve [CFR] <2.5) between men and women with HFpEF. We used lasso penalized regression to analyse 242 biomarkers … WebNov 30, 2024 · The non-phenomapping literature in HFpEF has importantly identified that regional adiposity and abdominal visceral and/or epicardial adipose tissue may be critical to the pathophysiology and outcomes of patients with HFpEF, compared to simply total body mass index, in USA and European cohorts. 48–51 In Asia, this cardiometabolic phenotype … builder meaning in telugu https://dacsba.com

Prevalenceand correlates of coronary …

WebPrevalenceand correlates of coronary microvasculardysfunction in heart failurewith preserved ejection fraction: PROMIS-HFpEF Sanjiv J. Shah1†, Carolyn S.P. Lam2,3†, Sara Svedlund4, Antti Saraste5, Camilla Hage6, Ru-San Tan2, Lauren Beussink-Nelson1, Maria Lagerstro¨m Fermer7, Malin A. Broberg7, Li-Ming Gan7,8,9*, and Lars H. Lund6* 1Division … WebFeb 1, 2024 · The PROMIS-HFpEF cohort is a highly selected cohort and assessment of . performance of the two scores in more general populations are desirable. In addition, the . WebAug 27, 2024 · Conclusions PROMIS-HFpEF is the first prospective multi-centre, multinational study to demonstrate a high prevalence of CMD in HFpEF in the absence of unrevascularized macrovascular CAD, and to ... builderment conveyor

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Category:CCI创新快讯 Ultromics公司的突破性设备EchoGo心衰系统获FDA批准 HFpEF…

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Promis-hfpef研究

Prevalence and correlates of coronary microvascular dysfunction in

WebJan 21, 2024 · Using the prospective multinational PROMIS-HFpEF study (Prevalence of Microvascular Dysfunction in HFpEF; n = 182; 54.6% women), we compared clinical and … WebThe PROMIS-Plus-HF measure comprises 86 items (64 existing; 22 new) across 18 domains. Internal consistency reliability (Cronbach α) coefficients ranged from 0.52 to 0.96, with …

Promis-hfpef研究

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Web文献「駆出率が保たれた心不全における冠微小循環障害と心不全入院および死亡率との関連性:promis-hfpef研究におけるフォローアップ」の詳細情報です。j-global 科学技術総合リンクセンターは研究者、文献、特許などの情報をつなぐことで、異分野の知や意外な発見などを支援する新しい ... WebAug 27, 2024 · This editorial refers to ‘Prevalence and correlates of coronary microvascular dysfunction in heart failure with preserved ejection fraction: PROMIS-HFpEF’ †, by S.J. Shah et al., on page 3439. There is increasing documentation that coronary microvascular dysfunction (CMD)-related subendocardial ischaemia contributes to left ventricular …

WebMar 15, 2024 · Change from baseline in KCCQ-PLS was defined as the endpoint value at week 16 minus the baseline value. KCCQ is a 23-item, self-administered instrument that quantifies physical function, symptoms (frequency, severity and recent change), social function, self-efficacy and knowledge, and quality of life.

WebApr 15, 2024 · 综上所述,该研究构建了一种全新的hfpef小鼠模型,高度复制了临床hfpef患者的病理表型。 以此为基础,揭示NLRP3炎症小体和线粒体功能障碍是HFpEF发生发展的重要驱动因素,并证实提升酮体β-OHB水平可调控上述线粒体-炎症环路,改善HFpEF症状( … WebWe analyzed blood samples and data from the PROMIS-HFpEF study (Prevalence of Microvascular Dysfunction in Heart Failure With Preserved Ejection Fraction), the design of which has been described previously.10 In brief, PROMIS-HFpEF was a multicenter, observational study to evaluate the prevalence and correlates of coronary microvascular …

WebJan 7, 2024 · The recent PROMIS-HFpEF trial was the first prospective, multinational, multicentre, observational study, which enrolled patients with HFpEF without obstructive CAD. ... Beyond the HFpEF paradigm, there is evidence that co-morbidities-associated chronic low-grade inflammation also can trigger endothelial-independent coronary …

Web入选中国住院患者心力衰竭注册研究(cn-hf)中符合hfpef诊断标准的患者,根据随访期间是否死亡分为死亡组和存活组。 从CN-HF中获得研究对象的人口学信息、入院时体格检查信息、入院首次超声心动图检查结果、实验室检查结果、合并症情况、用药情况和临床 ... builder mediationWebMay 13, 2024 · Consecutive steps of the comorbidity-inflammation paradigm were recently evaluated in the PROMIS-HFpEF study (PRevalence Of Microvascular dySfunction in HFpEF), 8 which performed a mediation analysis based on associations of comorbidities with cardiac structure/function, of comorbidities with inflammation and of inflammation with … builder mentalityWebNov 1, 2024 · Methods and Results. We assessed the 1-year outcomes in patients from the PROMIS-HFpEF study, a prospective observational study of patients with chronic stable HFpEF undergoing coronary flow reserve measurements. Outcomes were (1) time to cardiovascular (CV) death/first HF hospitalization, (2) CV death/recurrent HF … builderment androidWebMar 1, 2024 · A new stepwise diagnostic process, the ‘HFA–PEFF diagnostic algorithm’, is recommended, which includes assessment for heart failure symptoms and signs, typical clinical demographics, and diagnostic laboratory tests, electrocardiogram, and echocardiography. Making a firm diagnosis of chronic heart failure with preserved … crossword emotional shockWebJan 7, 2024 · According to recent epidemiologic data, approximately 50% of patients with heart failure (HF) have HF with preserved ejection fraction (HFpEF). Hypertension, obesity, … crossword employeeWebJun 29, 2024 · Recently, they defined a unique LA myopathy phenotype in HFpEF in the PROMIS-HFpEF observational study by taking the residuals of linear regression of LA … builder mccall idahoWebJun 24, 2024 · Based on invasive coronary angiography, three main conditions were identified: 1) obstructive epicardial CAD, 2) endothelium-independent CMD (by physiologic testing), and 3) endothelium-dependent CMD (by vasoreactivity testing). Based on CMRI, three main conditions were identified: 1) impaired myocardial perfusion, 2) myocardial … builderment balancer