Thy-1 promoter
Webb1 apr. 1990 · The functional domains of the murine Thy-1 gene promoter Article Apr 1991 Eugenia Spanopoulou Vincent Giguère Frank G Grosveld View Show abstract Systematic … WebbContains 6.5 kb of the murine thy1.2 gene, extending from the promoter to the intron following exon 4, but lacking exon 3 and its flanking introns (see Figure 1 in Caroni …
Thy-1 promoter
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Thy-1 or CD90 (Cluster of Differentiation 90) is a 25–37 kDa heavily N-glycosylated, glycophosphatidylinositol (GPI) anchored conserved cell surface protein with a single V-like immunoglobulin domain, originally discovered as a thymocyte antigen. Thy-1 can be used as a marker for a variety of stem cells and for … Visa mer The antigen Thy-1 was the first T cell marker to be identified. Thy-1 was discovered by Reif and Allen in 1964 during a search for heterologous antisera against mouse leukemia cells, and was demonstrated by … Visa mer Thy-1 has been conserved throughout vertebrate evolution and even in some invertebrates, with homologs described in many species like squid, frogs, chickens, mice Visa mer Thy-1 is one of the most heavily glycosylated membrane proteins with a carbohydrate content up to 30% of its molecular mass. … Visa mer As a GPI-anchored protein, Thy-1 is present in the outer leaflet of lipid rafts in the cell membrane. In case of neurons it is known to be expressed strongly in the mature axon. The axon hillock can act as a barrier for its lateral spread even though it has no transmembrane … Visa mer The 25-kDa core protein (excluding the heavy glycosylation) of rodent Thy-1 is 111 or 112 amino acids in length, and is N-glycosylated at three sites (In contrast to only two glycosylation sites for human Thy-1). The 162aa (murine, 161 for human) Thy1 … Visa mer Thy1 expression varies between species. Amongst the cells reported to generally express Thy-1 are thymocytes (precursor of T cells in the thymus) & CD34(+) prothymocytes; neurons, mesenchymal stem cells, hematopoietic stem cells, NK cells, … Visa mer The function of Thy-1 has not yet been fully elucidated. It has speculated roles in cell-cell and cell-matrix interactions, with implication in neurite outgrowth, nerve regeneration, apoptosis, metastasis, inflammation, and fibrosis. Role in cognition Visa mer Webb21 mars 2024 · THY1 (Thy-1 Cell Surface Antigen) is a Protein Coding gene. Diseases associated with THY1 include Retinal Artery Occlusion and Thymoma . Among its related …
WebbArticle Snippet: The Thy1-EGFP transgene mice expressing enhanced green fluorescent protein (EGFP) under the control of a modified regulatory region of the mouse thy1.2 … WebbThy-1/CD90 was first identified in 1964 on mouse T lymphocytes ( Reif and Allen, 1964a, b) and then on rat thymocytes and neural cells ( Barclay et al., 1976 ). Since then, more than 10, 000 publications refer to CD90 mainly …
Webb27 juli 2015 · As shown in Figure 3c, LPS decreased the amount of precipitated DNA associated with Ace-H4 at the Thy-1 promoter region when compared with the cells from control group (P<0.05), whereas ... Webb1 maj 2009 · The Thy-1 promoter has two elements that are traditionally attributed to “housekeeping” genes; specifically it is located within an area of high G/C content and has no classical TATA box [16, 56]. In addition, Thy-1 transcription initiates at multiple sites, and distribution of these sites differs in murine brain and thymus .
Webb21 mars 2024 · THY1 (Thy-1 Cell Surface Antigen) is a Protein Coding gene. Diseases associated with THY1 include Retinal Artery Occlusion and Thymoma . Among its related pathways are Metabolism of proteins and Integrin Pathway . Gene Ontology (GO) annotations related to this gene include protein kinase binding and GTPase activator …
WebbEleven Thy1-Cre lines exhibited transgene expression in several regions of the central and peripheral nervous systems, including the cerebral cortex, cerebellum, spinal cord, retina, … house cleaning in sparksWebb27 feb. 2024 · Thy-1 deficiency in endothelial cells and its impact on immune cell infiltration. MSCs Thy-1 has long been recognized solely as a marker of MSCs. Friedenstein et al. (65) first described MSCs as ad-herent, spindle-shaped cells isolated from the bone mar-row.Otherthanthebonemarrow,MSCscanalsobefound linq orderby groupbyWebbNational Center for Biotechnology Information linq pacemakerWebbThy1-YFP-16 mice express yellow fluorescent protein driven by a mouse Thy1 promoter, which labels sensory and motor neurons as well as subsets of central neurons. ... Figure 1A shows representative confocal fluorescence images of singly- and polyinnervated NMJs from C57BL/J6 and Thy-1-YFP-16 P9 mice. The morphological maturation (S1–S4) ... house cleaning in palm harborWebbThy-1 expression is suppressed in lungs of hypoxic mice and this is associated with increased TGFβ1 acti-vation [24]. Whether this suppression was due to in-creased DNA methylation in the Thy-1 promoter was not reported. Given the results from these studies investigating Thy-1 expression and regulation, along with our previous find- house cleaning in savannahWebb23 mars 2015 · Interestingly, the Thy-1 promoter is located in a high G/C content region, making it susceptible to DNA methylation, and there is evidence of Thy-1 suppression by promoter meth- ylation in lung fibroblasts (20, 24) and nasopharyngeal cancer cells (15). linqo trackWebb7 feb. 2024 · 2.1. PB-CRISPR enables robust knockout of protein-coding genes expressed in hPSCs. We designed an all-in-one PiggyBac system PB-CRISPR to deliver both hSpCas9 and gRNA, along with a puromycin-resistant gene for drug selection (Fig. 2 A).We first tested this system in protein-coding genes that are expressed in hPSCs (Fig. 2 B–H and … house cleaning in san mateo