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Thy1 promoter expression

WebbNational Center for Biotechnology Information Webb18 okt. 2012 · To generate GCaMP transgenic mice, we used the well-characterized Thy1 promoter to express GCaMPs in neurons. We generated eight founder lines of GCaMP2.2c and six founder lines of GCaMP3. Our previous studies have shown that the Thy1 promoter predominantly drives transgene expression in projection neurons in the CNS.

Thy1.2 YFP-16 Transgenic Mouse Labels a Subset of …

Webb24 sep. 2014 · Thy1 transgenics can exhibit transgene expression in specific subsets of cortical projection neurons . In GP5.3 mice L2, but not L3 cells, were labeled over large parts of the cortex; in the neocortex of … Webb11 apr. 2002 · Eleven Thy1-Cre lines exhibited transgene expression in several regions of the central and peripheral nervous systems, including the cerebral cortex, cerebellum, … knot today conditioner https://dacsba.com

Tissue expression of THY1 - Summary - The Human Protein Atlas

Webb15 jan. 1995 · The transgenic Thy1.1 RNA can be distinguished from the endogenous Thy1.2 RNA. which is slightly greater in size. Although we could detect no Thyl mRNA in peritoneal macrophages from nontransgenic littermates (Fig 4 A, lane 1), a very high level of expression was observed in the CD11b/Thy1.1 animal (Fig 4 A, lane 2). Webb1 okt. 2000 · Thy1 is an immunoglobulin superfamily member that is expressed by projection neurons in many parts of the nervous system, as well as by several … Webb6 apr. 2024 · We had previously shown that THY1 (CD90) is a tumor suppressor in nasopharyngeal carcinoma (NPC) and that its down-regulation and loss of expression … red frown face

Thy1 marks a distinct population of slow-cycling stem cells in the ...

Category:Thy1-Expressing Neurons in the Basolateral Amygdala May …

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Thy1 promoter expression

Thy1 promoter activity in the Rosa26 locus in mice: lessons from …

WebbCD90 is a membrane GPI-anchored protein with one Ig V-type superfamily domain that was initially described in mouse T cells. Besides the specific expression pattern and functions of CD90 that were described in normal … Webb7 feb. 2024 · Thy-1 plays a pathogenic role and is a potential biomarker for skin fibrosis in scleroderma. Age-related increase of alpha-synuclein oligomers is associated with motor disturbances in L61 transgenic mice.

Thy1 promoter expression

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Webb6 mars 2015 · First, we performed confocal microscopy of sensory ganglia from Thy1.2 YFP-16 mice and investigated the expression of TRPV1 using immunohistochemistry. As before YFP was expressed in many DRG and … Webb28 sep. 2016 · In summary, these results demonstrate that mutant PFN1 driven by the Thy1.2 promoter is expressed in the largest α motor neuron population, whereas the transgene expression is broader in Prp-PFN1 C71G and PrP-PFN1 WT mice, including both motor and nonmotor neurons. Fig. S1.

WebbEleven Thy1-Cre lines exhibited transgene expression in several regions of the central and peripheral nervous systems, including the cerebral cortex, cerebellum, spinal cord, retina, and dorsal root ganglion. Thy1-Cre expression also resulted in region-specific activation of Cre reporter transgenes. Webb18 okt. 2012 · Thy-1 Antigens / genetics Transfection Substances Calmodulin M13 protein (myosin light-chain kinase) Peptide Fragments Thy-1 Antigens Green Fluorescent …

WebbNational Center for Biotechnology Information Thy1 expression comes on when endothelial cells are activated. It has been shown to interact with the leukocyte integrin Mac1 (CD11b/CD18) and may play a role in leukocyte homing and recruitment. Modulating fibrosis. Role of Thy-1 in fibrosis and fibroblast differention may have some tissue variation. Visa mer Thy-1 or CD90 (Cluster of Differentiation 90) is a 25–37 kDa heavily N-glycosylated, glycophosphatidylinositol (GPI) anchored conserved cell surface protein with a single V-like immunoglobulin domain, originally discovered as a Visa mer The antigen Thy-1 was the first T cell marker to be identified. Thy-1 was discovered by Reif and Allen in 1964 during a search for … Visa mer The 25-kDa core protein (excluding the heavy glycosylation) of rodent Thy-1 is 111 or 112 amino acids in length, and is N-glycosylated at three sites (In contrast to only two glycosylation sites for human Thy-1). The 162aa (murine, 161 for human) Thy1 … Visa mer Thy1 expression varies between species. Amongst the cells reported to generally express Thy-1 are thymocytes (precursor of T cells in the thymus) & CD34(+) prothymocytes; Visa mer Thy-1 has been conserved throughout vertebrate evolution and even in some invertebrates, with homologs described in many species like squid, frogs, chickens, mice, rats, dogs, and humans. The Thy-1 gene is located at human chromosome 11q22.3 … Visa mer Thy-1 is one of the most heavily glycosylated membrane proteins with a carbohydrate content up to 30% of its molecular mass. Thy1 in most species has 3 N-glycosylation … Visa mer As a GPI-anchored protein, Thy-1 is present in the outer leaflet of lipid rafts in the cell membrane. In case of neurons it is known to be expressed strongly in the mature axon. The Visa mer

WebbIn this study, transgenic mice in which membrane-linked enhanced green fluorescent protein (mGFP) is expressed from the Thy1.2 promoter were used. In these mice, a …

Webb11 feb. 2024 · The Thy1 promoter targeted to the Rosa26 locus appeared active in virtually all Purkinje cells in the cerebellum and hippocampus. However, mosaic expression of the transgene under the Thy1... knot today kinky curlyWebb21 mars 2024 · THY1 (Thy-1 Cell Surface Antigen) is a Protein Coding gene. Diseases associated with THY1 include Retinal Artery Occlusion and Thymoma . Among its related pathways are Metabolism of proteins and Integrin Pathway . Gene Ontology (GO) annotations related to this gene include protein kinase binding and GTPase activator … knot today hair detanglerWebb21 okt. 2016 · Thy1-eNpHR carriers expressed significantly more fear throughout the session starting from the first tone, suggesting that inhibition of BLA Thy1 neurons … knot today lizzyWebb27 okt. 2014 · Thy1 is a glycosylphosphatidylinositol (GPI)-anchored, cell surface glycoprotein, which belongs to the immunoglobulin superfamily. Thy1 functions as a cell … knot today hair productsWebb8 aug. 2024 · As reported, Thy1 expression coupled with the established T cell gene, ... back-to-back Thy1 promoters were used in order to drive both CreERT2 and to specifically label neurons with EYFP. knot today productsWebb8 aug. 2024 · The expression of Thy1 in the epidermis, along with the expression of a CD3/V γ 3/V δ 1 TCR complex, has been characterized as a defining feature of dendritic … red frosted globe christmas lightsWebb3 okt. 2016 · The Thy-1 gene promoter resembles a "housekeeping" promoter in that it is located within a methylation-free island, lacks a canonical TATA box, and displays heterogeneity in the 5'-end termini of the mRNA. Using transgenic mice, we show that this promoter does not confer any tissue specificity and is active only in a position … red frs diffuser